Overview

  • Product nameAnti-CNNM4 antibody
    See all CNNM4 primary antibodies
  • Description
    Rabbit polyclonal to CNNM4
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide designed within residues: LLASRMENSP QFPIDGCTTH MENLAEKSEL PVVDETTTLL NERNSLLHKA, corresponding to internal sequence amino acids 720-769 of Human CNNM4 (NP_064569)

  • Positive control
    • 721_B cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab83105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 87 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/12500.

Target

  • FunctionProbable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.
  • Tissue specificityWidely expressed. Highly expressed in heart.
  • Involvement in diseaseDefects in CNNM4 are the cause of Jalili syndrome (JALIS) [MIM:217080]. A syndrome characterized by the association of cone-rod dystrophy and amelogenesis imperfecta.
  • Sequence similaritiesBelongs to the ACDP family.
    Contains 2 CBS domains.
    Contains 1 DUF21 domain.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 430430O18Rik antibody
    • ACDP4 antibody
    • Ancient conserved domain protein 4 antibody
    • Ancient conserved domain-containing protein 4 antibody
    • cnnm4 antibody
    • CNNM4_HUMAN antibody
    • Cyclin M4 antibody
    • Cyclin-M4 antibody
    • FLJ42791 antibody
    • KIAA1592 antibody
    • Metal transporter CNNM4 antibody
    see all

Anti-CNNM4 antibody images

  • Anti-CNNM4 antibody (ab83105) at 1 µg/ml + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 87 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 33 kDa. We are unsure as to the identity of these extra bands.

References for Anti-CNNM4 antibody (ab83105)

ab83105 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"