Anti-CNOT2 (phospho S101) antibody (ab111423)

Overview

  • Product nameAnti-CNOT2 (phospho S101) antibody
    See all CNOT2 primary antibodies
  • Description
    Rabbit polyclonal to CNOT2 (phospho S101)
  • SpecificityDetects endogenous levels of CNOT2 only when phosphorylated at serine 101.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from the Human CNOT2 protein (Q9NZN8) around the phosphorylation site of serine 101 (S-L-SP-Q-G).

  • Positive control
    • Human brain tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS without calcium and magnesium
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesAffinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111423 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionThe CCR4-NOT complex functions as general transcription regulation complex.
  • Tissue specificityUbiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes.
  • Sequence similaritiesBelongs to the CNOT2/3/5 family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCR4 associated factor 2 antibody
    • CCR4 NOT transcription complex subunit 2 antibody
    • CCR4-associated factor 2 antibody
    • CCR4-NOT transcription complex subunit 2 antibody
    • CDC36 antibody
    • CNOT2 antibody
    • CNOT2_HUMAN antibody
    • HSPC131 antibody
    • MSTP046 antibody
    • Negative regulator of transcription 2 antibody
    • NOT2 (negative regulator of transcription 2 yeast) homolog antibody
    • NOT2 antibody
    • NOT2H antibody
    see all

Anti-CNOT2 (phospho S101) antibody images

  • Immunohistochemistry analysis of paraffin-embedded human brain, using CNOT2 (Phospho-Ser101) Antibody (ab111423). The picture on the right is treated with the synthesized phospho peptide.

References for Anti-CNOT2 (phospho S101) antibody (ab111423)

ab111423 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"