Anti-CNOT6 antibody [2193C2a] (ab54376)

Overview

  • Product nameAnti-CNOT6 antibody [2193C2a]
    See all CNOT6 primary antibodies
  • Description
    Mouse monoclonal [2193C2a] to CNOT6
  • Tested applicationsSuitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    CCR4 NOT transcription complex subunit 6 recombinant C terminal fragment (Human)

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab54376 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
  • ClonalityMonoclonal
  • Clone number2193C2a
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab54376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 63 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • FunctionPoly(A) nuclease involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. Has 3'-5' RNase activity. The CCR4-NOT complex functions as general transcription regulation complex.
  • Sequence similaritiesBelongs to the CCR4/nocturin family.
    Contains 4 LRR (leucine-rich) repeats.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • A230103N10Rik antibody
    • AA407540 antibody
    • AW456442 antibody
    • carbon catabolite repression 4 protein antibody
    • Carbon catabolite repressor protein 4 homolog antibody
    • CCR4 antibody
    • CCR4 carbon catabolite repression 4 like antibody
    • CCR4 carbon catabolite repression 4-like antibody
    • CCR4-NOT transcription complex subunit 6 antibody
    • CCR4-NOT transcription complex, subunit 6 antibody
    • Cnot6 antibody
    • CNOT6_HUMAN antibody
    • Cytoplasmic deadenylase antibody
    • EC 3.1.-.- antibody
    • fa03c11 antibody
    • fc17f01 antibody
    • KIAA1194 antibody
    • MGC98472 antibody
    • OTTHUMP00000161544 antibody
    • wu:fa03c11 antibody
    • wu:fc17f01 antibody
    • zgc:65822 antibody
    see all

Anti-CNOT6 antibody [2193C2a] images

  • Anti-CNOT6 antibody [2193C2a] (ab54376) + CNOT6 recombinant fragment (immunogen)

    Predicted band size : 63 kDa

References for Anti-CNOT6 antibody [2193C2a] (ab54376)

ab54376 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (HeLa)
Specification HeLa
Fixative Paraformaldehyde
Permeabilization Yes - 0.5% Triton X100 in PBS
Username

Dr. Kirk McManus

Verified customer

Submitted Jun 26 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"