Overview

  • Product nameAnti-CNTROB antibody
    See all CNTROB primary antibodies
  • Description
    Rabbit polyclonal to CNTROB
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal sequence of Human CNTROB.

  • Positive control
    • Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab110916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionRequired for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
  • Tissue specificityWidely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
  • Developmental stagePreferentially incorporated into the newly assembled daughter centriole during centriole assembly at the late G1 or early S phase. Remains in the daughter centrioles throughout the cell cycle. At the next cycle of centriole duplication, its amount on the original daughter centriole eventually decreases.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm > cytoskeleton > centrosome > centriole. Centriole-associated, asymmetrically localizes to the daughter centriole.
  • Information by UniProt
  • Database links
  • Alternative names
    • 9830165K03Rik antibody
    • Centrobin antibody
    • centrobin, centrosomal BRCA2 interacting protein antibody
    • Centrosomal BRCA2 interacting protein antibody
    • Centrosomal BRCA2-interacting protein antibody
    • CNTRB_HUMAN antibody
    • Cntrob antibody
    • LIP8 antibody
    • LYST interacting protein 8 antibody
    • LYST-interacting protein 8 antibody
    • LYST-interacting protein LIP8 antibody
    • PP1221 antibody
    • RGD1307488 antibody
    • RP23 26L6.9 antibody
    see all

Anti-CNTROB antibody images

  • ab110916 at 1/50 dilution staining CNTROB in paraffin-embedded Human Brain tissue by Immunohistochemistry. The picture on the right is treated with the synthesized peptide.

References for Anti-CNTROB antibody (ab110916)

ab110916 has not yet been referenced specifically in any publications.

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