Overview

  • Product nameAnti-Cofilin antibody
    See all Cofilin primary antibodies
  • Description
    Rabbit polyclonal to Cofilin
  • Specificityab29038 recognises Cofilin 1. The immunogen sequence has only 3 amino acid differences from human Cofilin 2.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide (conjugated to KLH) corresponding to amino acid residues at the N terminus of human Cofilin 1.

  • Positive control
    • Jurkat cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab29038 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/2000.
WB 1/1000. Predicted molecular weight: 18 kDa.Can be blocked with Human Cofilin peptide (ab37634).

Target

  • FunctionControls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
  • Tissue specificityWidely distributed in various tissues.
  • Sequence similaritiesBelongs to the actin-binding proteins ADF family.
    Contains 1 ADF-H domain.
  • Post-translational
    modifications
    Phosphorylated on Ser-3 in resting cells.
  • Cellular localizationNucleus matrix. Cytoplasm > cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
  • Information by UniProt
  • Database links
  • Alternative names
    • 18 kDa phosphoprotein antibody
    • CFL 1 antibody
    • CFL antibody
    • CFL1 antibody
    • COF1_HUMAN antibody
    • Cofilin 1 antibody
    • Cofilin 1 non muscle antibody
    • Cofilin antibody
    • Cofilin non muscle isoform antibody
    • Cofilin-1 antibody
    • epididymis secretory protein Li 15 antibody
    • HEL-S-15 antibody
    • non-muscle isoform antibody
    • p18 antibody
    see all

Anti-Cofilin antibody images



  • Predicted band size : 18 kDa

References for Anti-Cofilin antibody (ab29038)

This product has been referenced in:
  • Kamal AH  et al. Investigation of adipocyte proteome during the differentiation of brown preadipocytes. J Proteomics 94:327-36 (2013). Read more (PubMed: 24129212) »
  • Codreanu SG  et al. Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal. Mol Cell Proteomics 8:670-80 (2009). WB ; Human . Read more (PubMed: 19054759) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab29038.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"