Overview

  • Product nameAnti-COG8 antibody
    See all COG8 primary antibodies
  • Description
    Mouse polyclonal to COG8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic COG8 peptide (Human) (AAH17492)

  • Positive control
    • COG8 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab69268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 27 kDa (predicted molecular weight: 23 kDa).

Target

  • RelevanceCOG8 is a component of the conserved oligomeric Golgi (COG) complex. This is a multiprotein complex that plays a structural role in the Golgi apparatus and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins and whose symptoms include severe psychomotor retardation, failure to thrive, seizures and dairy and wheat product intolerance. It is required for normal Golgi function.
  • Cellular localizationGolgi apparatus; Peripheral membrane protein.
  • Database links
  • Alternative names
    • COG complex subunit 8 antibody
    • Component of oligomeric golgi complex 8 antibody
    • Conserved oligomeric Golgi complex component 8 dependent on RIC1 antibody
    • DOR1 antibody

Anti-COG8 antibody images

  • All lanes : Anti-COG8 antibody (ab69268) at 1/500 dilution

    Lane 1 : COG8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 23 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)

    The transfected COG8 protein is a N-terminal fragment protein expected to run at 24.09 KDa

     

References for Anti-COG8 antibody (ab69268)

ab69268 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"