Overview

  • Product nameAnti-COL16A1 antibody
  • Description
    Rabbit polyclonal to COL16A1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen: FVSCIFPVPQ LFDLRWHKLM LSVAGRVASV HVDCSSASSQ PLGPRRPMRP VGHVFLGLDA EQGKPVSFDL QQVHIYCDPE LVLEEGCCEL LP, corresponding to amino acids 153-244 of Human COL16A1.

  • Positive control
    • Human gall bladder tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab121930 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionInvolved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology.
  • Tissue specificityIn papillary dermis, is a component of specialized fibrillin-1-containing microfibrils, whereas in territorial cartilage matrix, it is localized to a discrete population of thin, weakly banded collagen fibrils in association with other collagens (at protein level). In the placenta, where it is found in the amnion, a membranous tissue lining the amniotic cavity. Within the amnion, it is found in an acellular, relatively dense layer of a complex network of reticular fibers. Also located to a fibroblast layer beneath this dense layer. Exists in tissues in association with other types of collagen.
  • Sequence similaritiesBelongs to the fibril-associated collagens with interrupted helices (FACIT) family.
    Contains 1 TSP N-terminal (TSPN) domain.
  • Developmental stageTransiently elevated expression during gestation, and decrease at term.
  • DomainThis sequence defines eighteen different domains, nine triple-helical domains (COL9 to COL1) and ten non-triple-helical domains (NC10 to NC1). The numerous interruptions in the triple helix may make this molecule either elastic or flexible.
  • Post-translational
    modifications
    Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
    Glycosylated.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 447AA antibody
    • Alpha 1 type XVI collagen antibody
    • COGA1_HUMAN antibody
    • Col16a1 antibody
    • Collagen alpha-1(XVI) chain antibody
    • Collagen, type XVI, alpha 1 antibody
    • FP1572 antibody
    see all

Anti-COL16A1 antibody images

  • ab121930, at 1/2500 dilution, staining COL16A1 in paraffin embedded Human gall bladder tissue by Immunohistochemistry.
  • Immunohistochemical staining of Human placenta shows strong positivity in trophoblastic cells using ab121930

References for Anti-COL16A1 antibody (ab121930)

ab121930 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"