The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 64 kDa.
RelevanceBelongs to the fibril-associated collagens with interrupted helices (FACIT) family. collagen,type IX,alpha 3,fibril associated collagen with interrupted triple helices(FACIT), expressed in cartilage. Structural component of hyaline cartilage and vitreous of the eye.
Defects in COL9A3 are the cause of multiple epiphyseal dysplasia type 3 (EDM3), also known as multiple epiphyseal dysplasia with myopathy. EDM is a generalized skeletal dysplasia associated with significant morbidity. Joint pain, joint deformity, waddling gait, and short stature are the main clinical signs and symptoms. EDM is broadly categorized into the more severe Fairbank and the milder Ribbing types.