Colchicine from Colchicum autumnale (ab120663)

Overview

  • Product nameColchicine from Colchicum autumnale
  • Description
    Inhibitor of microtubule formation
  • Biological descriptionInhibitor of microtubule formation (Ki = 2.1 μM). Antimitotic, anti-inflammatory and antifibrotic activity. Unable to cross the blood-brain barrier.
  • Purity> 99%
  • General notes

    Light sensitive

Properties

    References for Colchicine from Colchicum autumnale (ab120663)

    This product has been referenced in:
    • Bhattacharyya B  et al. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin. Med Res Rev 28:155-83 (2008). Read more (PubMed: 17464966) »
    • Perez-Ramirez B  et al. Stoichiometric and substoichiometric inhibition of tubulin self-assembly by colchicine analogues. Biochemistry 35:3277-85 (1996). Read more (PubMed: 8605164) »
    • Cramer SF  et al. The mystique of the mistake. With proposed standards for validating proficiency tests in anatomic pathology. Am J Clin Pathol 96:774-7 (1991). Read more (PubMed: 1746496) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"