Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245)

Overview

  • Product nameAnti-Complex I subunit 8 kDa antibody [17C8E4E11]
  • Description
    Mouse monoclonal [17C8E4E11] to Complex I subunit 8 kDa
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human
  • Immunogen

    Bovine Complex I subunit 8 kDa.

  • Positive control
    • Isolated mitochondria from Human, Bovine, Rat and Mouse hearts.
  • General notes

    Product was previously marketed under the MitoSciences sub-brand.

Properties

Applications

Our Abpromise guarantee covers the use of ab110245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml.

Target

  • RelevanceCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • Cellular localizationMitochondrial
  • Database links
  • Alternative names
    • BC021616 antibody
    • CI 23k antibody
    • CI23KD antibody
    • MGC101957 antibody
    • MGC37950 antibody
    • NADH dehydrogenase (ubiquinone) Fe S protein 8, 23kDa (NADH coenzyme Q reductase) antibody
    • NADH ubiquinone oxidoreductase 23 kDa subunit antibody
    • TYKY antibody
    • TYKY subunit antibody
    see all

Anti-Complex I subunit 8 kDa antibody [17C8E4E11] images

  • All lanes : Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245) at 1 µg/ml

    Lane 1 : Human heart mitochondria at 10 µg
    Lane 2 : Bovine heart mitochondria at 4 µg
    Lane 3 : Rat heart mitochondria at 10 µg
    Lane 4 : Mouse heart mitochondria at 10 µg

References for Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245)

This product has been referenced in:
  • Hauser DN  et al. Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain. PLoS One 9:e94646 (2014). WB ; Mouse . Read more (PubMed: 24722488) »
  • Thomas RR  et al. Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18 (2011). Read more (PubMed: 20727424) »

See all 9 Publications for this product

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Thank you for your enquiry.

We did some workwith our sister companyMitoSciences trying to identify the target of this antibody and so far only managed to narrow down the targets within NDUFA5 and NDUFS6. It may be that we do further work on ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"