Overview

  • Product nameAnti-CORO1B antibody
    See all CORO1B primary antibodies
  • Description
    Rabbit polyclonal to CORO1B
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 450 and 489 of human CORO1B (NP_065174.1).

  • Positive control
    • Human Controls: Breast Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Stomach Carcinoma and Skin Squamous Cell Carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRegulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
    • Sequence similaritiesBelongs to the WD repeat coronin family.
      Contains 5 WD repeats.
    • Post-translational
      modifications
      Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Phosphorylation does not seem to affect subcellular location.
    • Cellular localizationCytoplasm > cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.
    • Information by UniProt
    • Database links
    • Alternative names
      • COR1B_HUMAN antibody
      • CORO 1B antibody
      • CORO1B antibody
      • Coronin 1B antibody
      • Coronin 2 antibody
      • Coronin actin binding protein 1B antibody
      • Coronin-1B antibody
      • Coronin-2 antibody
      • Coronin1B antibody
      • Coronin2 antibody
      • DKFZP762I166 antibody
      • OTTHUMP00000236823 antibody
      see all

    Anti-CORO1B antibody images

    • ab84558, at a 1/250 dilution, staining CORO1B in formalin fixed, paraffin embedded human prostate carcinoma by Immunohistochemistry, using DAB detection.
    • ab84558, at a 1/250 dilution, staining CORO1B in formalin fixed, paraffin embedded human stomach carcinoma by Immunohistochemistry, using DAB detection.

    References for Anti-CORO1B antibody (ab84558)

    ab84558 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab84558.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"