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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 54 kDa.
1/100 - 1/500.
Function Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
Sequence similarities Belongs to the WD repeat coronin family. Contains 5 WD repeats.
Post-translational modifications Phosphorylation by PKC on Ser-2 regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Phosphorylation does not seem to affect subcellular location.
Cellular localization Cytoplasm > cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers.
Information by UniProt
CORO 1B antibody
Anti-CORO1B antibody images
Western blot - CORO1B antibody (ab97650)
Anti-CORO1B antibody (ab97650) at 1/1000 dilution + A431 whole cell lysate at 30 µg Predicted band size : 54 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CORO1B antibody (ab97650)
ab97650 at 1/500 dilution staining CORO1B in paraffin-embedded H1299 xenograft by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
References for Anti-CORO1B antibody (ab97650)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"