• Product nameAnti-Coronin 1a antibody
    See all Coronin 1a primary antibodies
  • Description
    Rabbit polyclonal to Coronin 1a
  • Tested applicationsSuitable for: WB, IP, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat, Elephant
  • Immunogen

    Synthetic peptide (Human) corresponding to a region between residues 175 and 225 of Coronin 1a

  • Positive control
    • Jurkat whole cell lysate


Associated products


Our Abpromise guarantee covers the use of ab72212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Detects a band of approximately 55 kDa (predicted molecular weight: 51 kDa).
IP Use at 2-5 µg/mg of lysate.
IHC-P 1/200 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • FunctionMay be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
  • Tissue specificityExpressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.
  • Sequence similaritiesBelongs to the WD repeat coronin family.
    Contains 7 WD repeats.
  • Cellular localizationCytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cytoplasmic vesicle > phagosome membrane. In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification.
  • Information by UniProt
  • Database links
  • Alternative names
    • Actin binding protein antibody
    • CLABP antibody
    • Clipin A antibody
    • Clipin-A antibody
    • CLIPINA antibody
    • COR1A_HUMAN antibody
    • CORO1A antibody
    • Coronin 1 antibody
    • Coronin actin binding protein 1A antibody
    • Coronin like protein A antibody
    • Coronin like protein p57 antibody
    • Coronin-1A antibody
    • Coronin-like protein A antibody
    • Coronin-like protein p57 antibody
    • FLJ41407 antibody
    • HCORO1 antibody
    • MGC117380 antibody
    • OTTHUMP00000163017 antibody
    • p57 antibody
    • TACO antibody
    • Tryptophan aspartate containing coat protein antibody
    • Tryptophan aspartate-containing coat protein antibody
    see all

Anti-Coronin 1a antibody images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human stomach carcinoma tissue labelling Coronin 1a with ab72212 at 1/1000 (0.2µg/ml). Detection: DAB.
  • All lanes : Anti-Coronin 1a antibody (ab72212) at 0.04 µg/ml

    Lane 1 : Jurkat whole cell lysate at 50 µg
    Lane 2 : Jurkat whole cell lysate at 15 µg
    Lane 3 : Jurkat whole cell lysate at 5 µg

    developed using the ECL technique

    Predicted band size : 51 kDa

    Exposure time : 3 minutes
  • Immunoprecipitation analysis of  Jurkat whole cell lysate (1 mg for IP, 20% of IP loaded). ab72212 used for IP at 3 µg/mg lysate and for WB at 1 µg/ml. Lane 1 - ab72212 IP. Lane 2 - control IgG.

References for Anti-Coronin 1a antibody (ab72212)

ab72212 has not yet been referenced specifically in any publications.

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