Overview

  • Product nameAnti-Coronin 1a antibody
    See all Coronin 1a primary antibodies
  • Description
    Rabbit polyclonal to Coronin 1a
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region between residues 250 and 300 of Human Coronin 1a (NP_009005.1)

  • Positive control
    • human stomach adenocarcinoma, mouse fibroma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
    • Tissue specificityExpressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.
    • Sequence similaritiesBelongs to the WD repeat coronin family.
      Contains 7 WD repeats.
    • Cellular localizationCytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cytoplasmic vesicle > phagosome membrane. In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification.
    • Information by UniProt
    • Database links
    • Alternative names
      • Actin binding protein antibody
      • CLABP antibody
      • Clipin A antibody
      • Clipin-A antibody
      • CLIPINA antibody
      • COR1A_HUMAN antibody
      • CORO1A antibody
      • Coronin 1 antibody
      • Coronin actin binding protein 1A antibody
      • Coronin like protein A antibody
      • Coronin like protein p57 antibody
      • Coronin-1A antibody
      • Coronin-like protein A antibody
      • Coronin-like protein p57 antibody
      • FLJ41407 antibody
      • HCORO1 antibody
      • MGC117380 antibody
      • OTTHUMP00000163017 antibody
      • p57 antibody
      • TACO antibody
      • Tryptophan aspartate containing coat protein antibody
      • Tryptophan aspartate-containing coat protein antibody
      see all

    Anti-Coronin 1a antibody images

    • Detection of Human Coronin 1a by Immunohistochemistry on formalin fixed paraffin embedded section of Human stomach adenocarcinoma using 1/250 ab84504. Detection: DAB staining
    • Detection of mouse Coronin 1a by Immunohistochemistry on formalin fixed paraffin embedded section of Mouse fibroma using 1/250 ab84504. Detection: DAB staining

    References for Anti-Coronin 1a antibody (ab84504)

    ab84504 has not yet been referenced specifically in any publications.

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