Purification notesWhole antiserum is fractionated and then further purified by ion-exchange
chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 65-75 kDa.
Use at an assay dependent dilution.
FunctionContributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases.
Mammary tumor and squamous cell carcinoma associated antibody
Oncogene EMS1 antibody
p80/85 src substrate antibody
Src substrate cortactin antibody
References for Anti-Cortactin antibody (ab11066)
This product has been referenced in:
Albrechtsen R et al. Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity. Exp Cell Res317:195-209 (2011).
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