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Storage instructions Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Corresponding phospho antibody
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 85 kDa (predicted molecular weight: 62 kDa).
Function Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases.
Sequence similarities Contains 7 cortactin repeats. Contains 1 SH3 domain.
Domain The SH3 motif may mediate binding to the cytoskeleton.
Post-translational modifications Tyrosine phosphorylation in transformed cells may contribute to cellular growth regulation and transformation.
Cellular localization Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cell projection > ruffle. Associated with membrane ruffles and lamellipodia.
Information by UniProt
EMS 1 antibody
Anti-Cortactin antibody images
Western blot - Cortactin antibody (ab47582)
All lanes : Anti-Cortactin antibody (ab47582) at 1/500 dilution Lane 1 : Extracts from Hela cells treated with hydrogen peroxide. Lane 2 : Extracts from Hela cells treated with hydrogen peroxide and immunogenic peptide. Lysates/proteins at 30 µg per lane. Predicted band size : 62 kDa Observed band size : 85 kDa ( why is the actual band size different from the predicted?)
References for Anti-Cortactin antibody (ab47582)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"