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Storage instructions Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab51101 affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 80 kDa).
Function Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases.
Sequence similarities Contains 7 cortactin repeats. Contains 1 SH3 domain.
Domain The SH3 motif may mediate binding to the cytoskeleton.
Post-translational modifications Tyrosine phosphorylation in transformed cells may contribute to cellular growth regulation and transformation.
Cellular localization Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cell projection > ruffle. Associated with membrane ruffles and lamellipodia.
Information by UniProt
EMS 1 antibody
Anti-Cortactin antibody images
Western blot - Cortactin antibody (ab51101)
References for Anti-Cortactin antibody (ab51101)
has not yet been referenced specifically in any publications.
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