Anti-Cortical Thymocytes antibody [ICO-44] (ab24235)

Overview

  • Product name
    Anti-Cortical Thymocytes antibody [ICO-44]
  • Description
    Mouse monoclonal [ICO-44] to Cortical Thymocytes
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation (Human): peripheral blood lymphocytes.

Properties

Applications

Our Abpromise guarantee covers the use of ab24235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Relevance
    CTXL, a cortical thymocyte marker is a member of the immunoglobulin (Ig) superfamily and has features of both antigen specific receptors and adhesion molecules. This protein contains a signal peptide, an extracellular V type Ig like domain followed by a C2 type Ig like domain, a transmembrane region devoid of charged residues, and a cytoplasmic tail. There are multiple N glycosylation sites in the extracellular region and phosphorylation sites in the cytoplasmic tail. Northern blot analysis revealed CTH expression in stomach, colon, prostate, trachea, and thyroid gland, with lower levels in bladder and lung. CTH expression was not detected in thymus, although CTH could be amplified by PCR from a thymus cDNA library.
  • Cellular localization
    Type I membrane protein.
  • Database links
  • Alternative names
    • Cortical thymocyte like protein antibody
    • CT like protein antibody
    • CTH antibody
    • CTXL antibody
    • Vset and immunoglobulin domain containing 2 antibody
    • VSIG2 antibody
    see all

References

ab24235 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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