Anti-Corticotropin Releasing Factor antibody (ab80360)

Overview

  • Product name
    Anti-Corticotropin Releasing Factor antibody
    See all Corticotropin Releasing Factor primary antibodies
  • Description
    Chicken polyclonal to Corticotropin Releasing Factor
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Pig
  • Immunogen

    Recombinant fragment: EAPERERRSE EPPISLDLTF HLLREVLEMA RAEQLAQQAH SNRKLMEIIG K, corresponding to amino acids 146-196 of Human Corticotropin Releasing Factor derived from E. coli.

  • Positive control
    • E. coli derived Corticotropin Releasing Factor fusion protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab80360 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/3000. Predicted molecular weight: 21 kDa.

Target

  • Relevance
    CRF precursor is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRF is a neuroendocrine hormone secreted by the paraventricular nucleus (PVN) of the hypothalamus and is a key player in the hypothalamic pituitary adrenal axis. It is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. Neuronal CRF is important in a variety of diverse roles including, memory, depression, stress, kidney function, parturition, metabolism and feeding (to mention a few).
  • Cellular localization
    Cytoplasmic and Secreted
  • Database links
  • Alternative names
    • Corticoliberin antibody
    • Corticotropin releasing factor antibody
    • Corticotropin releasing hormone antibody
    • CRF antibody
    • Crh antibody
    • CRH1 antibody
    see all

Images

  • Anti-Corticotropin Releasing Factor antibody (ab80360) at 1/3000 dilution + E. coli derived Corticotropin Releasing Factor fusion protein at 0.4 µg

    Secondary
    goat-anti-IgY/Fc-HRP at 1/10000 dilution
    Developed using the ECL technique

    Predicted band size : 21 kDa
    Observed band size : 15 kDa (why is the actual band size different from the predicted?)

References

ab80360 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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