Anti-Cortisol antibody [F4P1A3] (ab116600)
Key features and details
- Mouse monoclonal [F4P1A3] to Cortisol
- Suitable for: ELISA, IP, RIA
- Isotype: IgG2b
Overview
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Product name
Anti-Cortisol antibody [F4P1A3]
See all Cortisol primary antibodies -
Description
Mouse monoclonal [F4P1A3] to Cortisol -
Host species
Mouse -
Tested applications
Suitable for: ELISA, IP, RIAmore details -
Immunogen
Cortisol-3-CMO conjugated to BSA.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 0.019% Potassium chloride, 0.79% Sodium chloride, 0.14% Potassium phosphate, 0.1% BSA, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
F4P1A3 -
Isotype
IgG2b -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab116600 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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RIA |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
RIA
Use at an assay dependent concentration. |
Target
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Relevance
Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism. -
Cellular localization
Secreted
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab116600 has not yet been referenced specifically in any publications.