Anti-COX1 / Cyclooxygenase 1 antibody (ab22720)

Overview

  • Product nameAnti-COX1 / Cyclooxygenase 1 antibodySee all COX1 / Cyclooxygenase 1 primary antibodies ...
  • Description
    Goat polyclonal to COX1 / Cyclooxygenase 1
  • Specificityab22720 reacts with Prostaglandin H Synthase-1 (PGHS-1, Cox-1).
  • Tested applicationsIHC-P, WB more details
  • Species reactivity
    Reacts with: Mouse, Rat, Sheep, Human
  • Immunogen

    Full length native protein (purified) (Sheep). Purified Sheep Cox-1

Applications

Our Abpromise guarantee covers the use of ab22720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
WB
  • Application notesIHC-P: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 69 kDa. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
    • PathwayLipid metabolism; prostaglandin biosynthesis.
    • Sequence similaritiesBelongs to the prostaglandin G/H synthase family.
      Contains 1 EGF-like domain.
    • Cellular localizationMicrosome membrane. Endoplasmic reticulum membrane.
    • Target information above from: UniProt accession P23219 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • Alternative names
      • COX 1 antibody
      • COX 3 antibody
      • COX-1 antibody
      • COX1 antibody
      • COX3 antibody
      • COX3 antibody
      • Cyclooxygenase 1 antibody
      • Cyclooxygenase 3, included antibody
      • Cyclooxygenase-1 antibody
      • Cyclooxygenase1 antibody
      • EC 1.14.99.1 antibody
      • Partial COX1 proteins, included antibody
      • PCOX 1 antibody
      • PCOX1 antibody
      • PCOX1 antibody
      • PGG/HS antibody
      • PGG/HS antibody
      • PGH synthase 1 antibody
      • PGH1_HUMAN antibody
      • PGHS 1 antibody
      • PGHS-1 antibody
      • PGHS1 antibody
      • PGHS1 antibody
      • PHS 1 antibody
      • PHS1 antibody
      • PHS1 antibody
      • Prostaglandin endoperoxide synthase 1 antibody
      • Prostaglandin endoperoxide synthase 1 antibody
      • Prostaglandin G/H synthase 1 antibody
      • Prostaglandin G/H synthase and cyclooxygenase antibody
      • Prostaglandin G/H synthase and cyclooxygenase antibody
      • Prostaglandin H Synthase 1 antibody
      • Prostaglandin H2 synthase 1 antibody
      • Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody
      • Prostaglandin-endoperoxide synthase 1 antibody
      • PTGHS antibody
      • PTGHS antibody
      • PTGS 1 antibody
      • PTGS1 antibody
      • PTGS1 antibody
      see all

    Anti-COX1 / Cyclooxygenase 1 antibody images

    • IHC image of ab22720 staining in human breast carcinoma formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab22720, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

      For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

    References for Anti-COX1 / Cyclooxygenase 1 antibody (ab22720)

    ab22720 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"