Anti-COX1 / Cyclooxygenase 1 antibody (ab2338)

Overview

  • Product nameAnti-COX1 / Cyclooxygenase 1 antibodySee all COX1 / Cyclooxygenase 1 primary antibodies ...
  • Description
    Goat polyclonal to COX1 / Cyclooxygenase 1
  • SpecificityThis antibody is expected to recognise both human isoforms of this protein.
  • Tested applicationsWB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide: QDDGPAVERPSTEL, corresponding to C terminal amino acids 586-599 of Human COX1/ Cyclooxygenase 1.

  • General notesPrincipal Names – PTGS1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); COX1; PHS 1; PTGHS; PGG/HS; PGHS-1; prostaglandin G/H synthase and cyclooxygenase; COX3; PCOX1 Official Gene Symbol - PTGS1 GenBank Accession Number – NP_000953; NP_542158 LocusLink ID - 5742 Gene Ontology terms - Lipid metabolism; physiological processes; prostaglandin-endoperoxide synthase

Properties

Applications

Our Abpromise guarantee covers the use of ab2338 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Can be blocked with Human COX1 / Cyclooxygenase 1 peptide (ab22901).
ELISA 1/32000.
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • FunctionMay play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
  • PathwayLipid metabolism; prostaglandin biosynthesis.
  • Sequence similaritiesBelongs to the prostaglandin G/H synthase family.
    Contains 1 EGF-like domain.
  • Cellular localizationMicrosome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • COX 1 antibody
    • COX 3 antibody
    • COX-1 antibody
    • COX1 antibody
    • COX3 antibody
    • Cyclooxygenase 1 antibody
    • Cyclooxygenase 3, included antibody
    • Cyclooxygenase-1 antibody
    • Cyclooxygenase1 antibody
    • EC 1.14.99.1 antibody
    • Partial COX1 proteins, included antibody
    • PCOX 1 antibody
    • PCOX1 antibody
    • PGG/HS antibody
    • PGH synthase 1 antibody
    • PGH1_HUMAN antibody
    • PGHS 1 antibody
    • PGHS-1 antibody
    • PGHS1 antibody
    • PHS 1 antibody
    • PHS1 antibody
    • Prostaglandin endoperoxide synthase 1 antibody
    • Prostaglandin G/H synthase 1 antibody
    • Prostaglandin G/H synthase and cyclooxygenase antibody
    • Prostaglandin H Synthase 1 antibody
    • Prostaglandin H2 synthase 1 antibody
    • Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody
    • Prostaglandin-endoperoxide synthase 1 antibody
    • PTGHS antibody
    • PTGS 1 antibody
    • PTGS1 antibody
    see all

Anti-COX1 / Cyclooxygenase 1 antibody images

  • Ab2338 staining (1µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • ab2338 (3.8 µg/ml) staining COX1/cyclooxygenase 1 in paraffin-embedded Human heart myocardial fibers following steamed antigen retrieval with citrate buffer (pH 6).

References for Anti-COX1 / Cyclooxygenase 1 antibody (ab2338)

ab2338 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Human Cell lysate - other (Hela cells, microsome)
Loading amount 120 µg
Specification Hela cells, microsome
Gel Running Conditions Reduced Denaturing (4-12% gel)
Blocking step Milk as blocking agent for 14 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
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Submitted Apr 17 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"