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Goat polyclonal to COX1 / Cyclooxygenase 1
This antibody is expected to recognise both human isoforms of this protein.
Synthetic peptide: QDDGPAVERPSTEL, corresponding to C terminal amino acids 586-599 of Human COX1/ Cyclooxygenase 1.
Principal Names – PTGS1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); COX1; PHS 1; PTGHS; PGG/HS; PGHS-1; prostaglandin G/H synthase and cyclooxygenase; COX3; PCOX1
Official Gene Symbol - PTGS1
GenBank Accession Number – NP_000953; NP_542158
LocusLink ID - 5742
Gene Ontology terms - Lipid metabolism; physiological processes; prostaglandin-endoperoxide synthase
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 - 3 µg/ml. Can be blocked with Human COX1 / Cyclooxygenase 1 peptide (ab22901).
||Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
Lipid metabolism; prostaglandin biosynthesis.
Belongs to the prostaglandin G/H synthase family.
Contains 1 EGF-like domain.
Microsome membrane. Endoplasmic reticulum membrane.
Information by UniProt
- COX 1 antibody
- COX 3 antibody
- COX-1 antibody
Western blot - COX1 / Cyclooxygenase 1 antibody (ab2338)
Ab2338 staining (1µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - COX1 / Cyclooxygenase 1 antibody (ab2338)
ab2338 (3.8 µg/ml) staining COX1/cyclooxygenase 1 in paraffin-embedded Human heart myocardial fibers following steamed antigen retrieval with citrate buffer (pH 6).
has not yet been referenced specifically in any publications.
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