Anti-COX2 / Cyclooxygenase 2 antibody (ab15191)

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ab15191 has been referenced in 43 publications.

  • Simonsson M  et al. The prognostic impact of COX-2 expression in breast cancer depends on oral contraceptive history, preoperative NSAID use, and tumor size. Int J Cancer 140:163-175 (2017). PubMed: 27632554
  • Tang SH  et al. Expression of cyclooxygenase-2 is correlated with lncRNA-COX-2 in cirrhotic mice induced by carbon tetrachloride. Mol Med Rep 15:1507-1512 (2017). IHC-P ; Mouse . PubMed: 28259935
  • Calvello R  et al. Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation. Front Neurol 8:251 (2017). WB ; Mouse . PubMed: 28649222
  • Farrell JS  et al. Postictal behavioural impairments are due to a severe prolonged hypoperfusion/hypoxia event that is COX-2 dependent. Elife 5:N/A (2016). IHC ; Rat . PubMed: 27874832
  • Jiang ZX  et al. Roscovitine ameliorates endotoxin-induced uveitis through neutrophil apoptosis. Mol Med Rep 14:1083-90 (2016). WB ; Mouse . PubMed: 27279017
  • Hosono K  et al. Signaling of Prostaglandin E Receptors, EP3 and EP4 Facilitates Wound Healing and Lymphangiogenesis with Enhanced Recruitment of M2 Macrophages in Mice. PLoS One 11:e0162532 (2016). PubMed: 27711210
  • Wang H  et al. Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc. Carcinogenesis 37:723-30 (2016). PubMed: 27207656
  • Afroze SH  et al. Apoptotic and stress signaling markers are augmented in preeclamptic placenta and umbilical cord. BBA Clin 6:25-30 (2016). PubMed: 27335802
  • Thirunavukkarasu S  et al. Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice. Am J Pathol N/A:N/A (2016). IHC . PubMed: 27301358
  • Mishra PS  et al. Astroglia acquires a toxic neuroinflammatory role in response to the cerebrospinal fluid from amyotrophic lateral sclerosis patients. J Neuroinflammation 13:212 (2016). WB ; Rat . PubMed: 27578023
  • Tonade D  et al. Photoreceptor Cells Produce Inflammatory Mediators That Contribute to Endothelial Cell Death in Diabetes. Invest Ophthalmol Vis Sci 57:4264-71 (2016). Mouse . PubMed: 27548900
  • Abu N  et al. Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro. BMC Complement Altern Med 16:86 (2016). WB . PubMed: 26922065
  • de la Rica L  et al. NF-?B-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation. Genome Biol 16:2 (2015). WB . PubMed: 25601191
  • Kaczocha M  et al. Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms. Mol Pain 11:52 (2015). WB ; Mouse . PubMed: 26311517
  • Wang J  et al. Mechanism of QSYQ on anti-apoptosis mediated by different subtypes of cyclooxygenase in AMI induced heart failure rats. BMC Complement Altern Med 15:352 (2015). WB ; Rat . PubMed: 26445960
  • Wang J  et al. Qishenyiqi Dropping Pill attenuates myocardial fibrosis in rats by inhibiting RAAS-mediated arachidonic acid inflammation. J Ethnopharmacol 176:375-84 (2015). WB ; Rat . PubMed: 26590099
  • Papaconstantinou J  et al. Attenuation of p38a MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells. Aging (Albany NY) 7:718-33 (2015). IHC-P ; Mouse . PubMed: 26423835
  • Choi DI  et al. Ethanol Extract of Peanut Sprout Exhibits a Potent Anti-Inflammatory Activity in Both an Oxazolone-Induced Contact Dermatitis Mouse Model and Compound 48/80-Treated HaCaT Cells. Ann Dermatol 27:142-51 (2015). WB ; Human . PubMed: 25834352
  • Xiao H  et al. ?-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1a/VEGF pathways under hypoxic condition. Oncotarget 6:2180-92 (2015). Human . PubMed: 25537504
  • Hayes EM  et al. Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes. Front Immunol 5:537 (2014). IHC-P ; Mouse . PubMed: 25389425
  • Takechi R  et al. Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction. Lipids Health Dis 13:91 (2014). Mouse . PubMed: 24890126
  • Hayashi A  et al. Inflammatory suppressive effect of prostate cancer cells with prolonged exposure to transforming growth factor ß on macrophage-differentiated cells via downregulation of prostaglandin E2. Oncol Lett 8:1513-1518 (2014). WB ; Human . PubMed: 25202359
  • Markkula A  et al. Impact of COX2 genotype, ER status and body constitution on risk of early events in different treatment groups of breast cancer patients. Int J Cancer 135:1898-910 (2014). PubMed: 24599585
  • Peacock O  et al. Inflammation and MiR-21 pathways functionally interact to downregulate PDCD4 in colorectal cancer. PLoS One 9:e110267 (2014). WB ; Human . PubMed: 25310697
  • Rocha SW  et al. Diethylcarbamazine reduces chronic inflammation and fibrosis in carbon tetrachloride- (CCl4-) induced liver injury in mice. Mediators Inflamm 2014:696383 (2014). IHC ; Mouse . PubMed: 25374445
  • Villa V  et al. Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells. Mol Neurobiol N/A:N/A (2014). PubMed: 25404089
  • Balamurugan K  et al. FBXW7a attenuates inflammatory signalling by downregulating C/EBPd and its target gene Tlr4. Nat Commun 4:1662 (2013). PubMed: 23575666
  • Lin DP  et al. Assessment of ultraviolet B-blocking effects of weekly disposable contact lenses on corneal surface in a mouse model. Mol Vis 19:1158-68 (2013). IHC-P ; Mouse . PubMed: 23734085
  • Takahashi S  et al. Phospholipase A2 expression in coronary thrombus is increased in patients with recurrent cardiac events after acute myocardial infarction. Int J Cardiol 168:4214-21 (2013). PubMed: 23948114
  • Chhor V  et al. Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro. Brain Behav Immun 32:70-85 (2013). ICC/IF ; Mouse . PubMed: 23454862
  • Altay O  et al. Effects of isoflurane on brain inflammation after subarachnoid hemorrhage in mice. Neurobiol Dis N/A:N/A (2013). PubMed: 24084689
  • Shi JD  et al. Tocopherol supplementation reduces NO production and pulmonary inflammatory response to bleomycin. Nitric Oxide 34:27-36 (2013). IHC ; Mouse . PubMed: 23669183
  • Miyoshi J  et al. 5-aminosalicylic acid mediates expression of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase to suppress colorectal tumorigenesis. Anticancer Res 32:1193-202 (2012). WB . PubMed: 22493349
  • Nilsson L  et al. Disruption of cyclooxygenase-2 prevents downregulation of cortical AQP2 and AQP3 in response to bilateral ureteral obstruction in the mouse. Am J Physiol Renal Physiol 302:F1430-9 (2012). WB ; Mouse . PubMed: 22397925
  • Domitrovic R  et al. Differential hepatoprotective mechanisms of rutin and quercetin in CCl(4)-intoxicated BALB/cN mice. Acta Pharmacol Sin 33:1260-70 (2012). PubMed: 22902988
  • Park CY  et al. Cyclooxygenase-2-expressing macrophages in human pterygium co-express vascular endothelial growth factor. Mol Vis 17:3468-80 (2011). WB ; Human . PubMed: 22219642
  • Kim J  et al. Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease. Hum Mol Genet 19:3919-35 (2010). ICC/IF ; Human . PubMed: 20660112
  • Broom OJ  et al. CD47 regulates collagen I-induced cyclooxygenase-2 expression and intestinal epithelial cell migration. PLoS One 4:e6371 (2009). PubMed: 19636412
  • Gimelli S  et al. The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma. Mol Cancer 8:52 (2009). IHC-P ; Human . PubMed: 19642973
  • Sreevidya CS  et al. Inhibition of photocarcinogenesis by platelet-activating factor or serotonin receptor antagonists. Cancer Res 68:3978-84 (2008). IHC-Fr ; Mouse . PubMed: 18483284
  • Gong R  et al. Co-localization of glucocorticoid metabolizing and prostaglandin synthesizing enzymes in rat kidney and liver. Life Sci 83:725-31 (2008). PubMed: 18930067
  • Parhamifar L  et al. Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells. Carcinogenesis 26:1988-98 (2005). PubMed: 15975962
  • Baserga M  et al. Uteroplacental insufficiency alters hepatic expression, phosphorylation, and activity of the glucocorticoid receptor in fetal IUGR rats. Am J Physiol Regul Integr Comp Physiol 289:R1348-53 (2005). PubMed: 16002560


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