Overview

  • Product name
  • Description
    Rabbit polyclonal to CP110
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from the Center region of Human CP110.

  • Positive control
    • HL-60 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab91415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 113 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Necessary for centrosome duplication at different stages of procentriole formation. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.
    • Tissue specificity
      Highly expressed in testis. Detected at intermediate levels in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
    • Post-translational
      modifications
      Phosphorylated by CDKs.
      Ubiquitinated by the SCF(Cyclin F) during G2 phase, leading to its degradation by the proteasome and preventing centrosome reduplication.
    • Cellular localization
      Cytoplasm > cytoskeleton > centrosome > centriole. Recruited early and then associates with the growing distal tips.
    • Information by UniProt
    • Database links
    • Alternative names
      • 110 kDa centrosomal protein antibody
      • CCP110 antibody
      • Centriolar coiled coil protein 110kDa antibody
      • Centrosomal protein 110 kDa antibody
      • Centrosomal protein CP110 antibody
      • Centrosomal protein of 110 kDa antibody
      • Cep110 antibody
      • CP110 antibody
      • CP110_HUMAN antibody
      • DKFZp781G1416 antibody
      • FAN antibody
      • KIAA0419 antibody
      see all

    Images

    • Anti-CP110 antibody (ab91415) at 1/100 dilution + HL-60 cell line lysates at 35 µg

      Predicted band size : 113 kDa

    References

    ab91415 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab91415.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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