Overview

  • Product name
  • Description
    Rabbit polyclonal to CP2c
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Xenopus laevis, Pufferfish
  • Immunogen

    Synthetic peptide: GAYSMSDVLA LPIFKQEESS LPPDNENKIL PFQYVLCAAT SPAVKLHDET , corresponding to N terminal amino acids 37-86 of Human CP2c

  • Positive control
    • 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab80445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
  • Tissue specificity
    Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level).
  • Sequence similarities
    Belongs to the grh/CP2 family. CP2 subfamily.
  • Developmental stage
    Expressed in fetal erythroid tissue.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha globin transcription factor CP2 antibody
    • Alpha-globin transcription factor CP2 antibody
    • CP2 antibody
    • Late SV40 factor antibody
    • LBP 1C antibody
    • LBP1C antibody
    • LSF antibody
    • LSF1D antibody
    • SAA3 enhancer factor antibody
    • SEF antibody
    • TFCP2 antibody
    • TFCP2_HUMAN antibody
    • TFCP2C antibody
    • Transcription factor CP2 antibody
    • Transcription factor LSF antibody
    see all

Images

  • Anti-CP2c antibody (ab80445) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 57 kDa
    Observed band size : 57 kDa

References

This product has been referenced in:
  • Teperek M  et al. Sperm and spermatids contain different proteins and bind distinct egg factors. Int J Mol Sci 15:16719-40 (2014). WB ; Frog . Read more (PubMed: 25244019) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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