Overview

  • Product name
    CPCCOEt
  • Description
    Selective, non-competitive mGlu1 antagonist
  • Biological description
    Potent, selective non-competitive mGlu1 metabotropic glutamate receptor antagonist (IC50 = 6.5 μM at hmGluR1 with no activity at hmGluR2, -4a, -5a, -7b, and -8a up to 100 μM).
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Litschig S  et al. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding. Mol Pharmacol 55:453-61 (1999). Read more (PubMed: 10051528) »
  • Hermans E  et al. Reversible and non-competitive antagonist profile of CPCCOEt at the human type 1alpha metabotropic glutamate receptor. Neuropharmacology 37:1645-7 (1998). Read more (PubMed: 9886688) »

See all 14 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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