Anti-CPLX1 antibody (ab15855)

Overview

• Product nameAnti-CPLX1 antibody
  See all CPLX1 primary antibodies
• Description
  Chicken polyclonal to CPLX1
• Tested applicationsSuitable for: WBmore details
• Species reactivity
  Reacts with: Mouse, Rat, Cow, Human
  
• Immunogen

  Amino acids 1-134 of CPLX1.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• ClonalityPolyclonal
• IsotypeIgY
• Research areas
  • Neuroscience
  • Neurotransmission
  • Secretory Vesicles
  • SNAPs & SNAREs

  • Signal Transduction
  • Protein Trafficking
  • Vesicle Transport
  • SNAPs & SNAREs

  • Neuroscience
  • Cell Type Marker
  • Neuron marker
  • Synapse marker

Applications

Target

• FunctionPositively regulates a late step in synaptic vesicle exocytosis. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells.
• Tissue specificityNervous system. In hippocampus and cerebellum, expressed mainly by inhibitory neurons. Overexpressed in substantia nigra from patients with Parkinson disease.
• Sequence similaritiesBelongs to the complexin/synaphin family.
• Cellular localizationCytoplasm > cytosol. Enriched at synaptic-releasing sites in mature neurons.

• Target information above from: UniProt accession O14810 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 768228 Cow
  • Entrez Gene: 10815 Human
  • Entrez Gene: 12889 Mouse
  • Entrez Gene: 64832 Rat
  • Omim: 605032 Human
  • SwissProt: Q0IIL7 Cow
  • SwissProt: O14810 Human
  • SwissProt: P63040 Mouse

  • SwissProt: P63041 Rat
  • Unigene: 478930 Human
  • Unigene: 5195 Mouse
  • Unigene: 10133 Rat

  see all
• Alternative names
  • 921-S antibody
  • complexin 1 antibody
  • Complexin I antibody

  • Complexin-1 antibody
  • CPLX1 antibody
  • CPLX1_HUMAN antibody
  • CPX I antibody
  • CPX-I antibody
  • CPX1 antibody
  • Synaphin 2 antibody
  • Synaphin-2 antibody

  see all