Anti-CPT1A antibody - Carboxyterminal end (ab71466)

Overview

  • Product nameAnti-CPT1A antibody - Carboxyterminal end
    See all CPT1A primary antibodies
  • Description
    Rabbit polyclonal to CPT1A - Carboxyterminal end
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from the C terminal region of human CPT1A.

  • Positive control
    • Y79 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab71466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Detects bands of approximately 46, 60, 70 and 90 kDa (predicted molecular weight: 88 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Tissue specificityStrong expression in kidney and heart, and lower in liver and skeletal muscle.
    • PathwayLipid metabolism; fatty acid beta-oxidation.
    • Involvement in diseaseDefects in CPT1A are the cause of carnitine palmitoyltransferase 1A deficiency (CPT1AD) [MIM:255120]; also known as CPT-I deficiency or CPT1A deficiency. CPT1AD is a rare autosomal recessive metabolic disorder of long-chain fatty acid oxidation characterized by severe episodes of hypoketotic hypoglycemia usually occurring after fasting or illness. Onset is in infancy or early childhood.
    • Sequence similaritiesBelongs to the carnitine/choline acetyltransferase family.
    • Cellular localizationMitochondrion outer membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Carnitine O palmitoyltransferase 1 liver isoform antibody
      • Carnitine O palmitoyltransferase I antibody
      • Carnitine O palmitoyltransferase I liver isoform antibody
      • Carnitine O-palmitoyltransferase 1 antibody
      • Carnitine O-palmitoyltransferase I antibody
      • Carnitine palmitoyltransferase 1A (liver) antibody
      • Carnitine palmitoyltransferase 1A antibody
      • Carnitine palmitoyltransferase I antibody
      • Carnitine palmitoyltransferase I liver antibody
      • CPT 1 antibody
      • CPT I antibody
      • CPT1 antibody
      • CPT1 L antibody
      • CPT1-L antibody
      • Cpt1a antibody
      • CPT1A_HUMAN antibody
      • CPTI antibody
      • CPTI-L antibody
      • L CPT1 antibody
      • liver isoform antibody
      see all

    Anti-CPT1A antibody - Carboxyterminal end images

    • Anti-CPT1A antibody - Carboxyterminal end (ab71466) at 1/100 dilution + Y79 cell line lysate at 35 µg

      Predicted band size : 88 kDa
      Observed band size : 90 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 46 kDa,60 kDa,70 kDa. We are unsure as to the identity of these extra bands.

    References for Anti-CPT1A antibody - Carboxyterminal end (ab71466)

    ab71466 has not yet been referenced specifically in any publications.

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