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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: 0.09% Sodium Azide
Concentration information loading...
Purity Protein G purified
Purification notes This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes ELISA: 1/1000.
WB: 1/100 - 1/500. Detects bands of approximately 46, 60, 70 and 90 kDa (predicted molecular weight: 88 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Tissue specificity Strong expression in kidney and heart, and lower in liver and skeletal muscle.
Pathway Lipid metabolism; fatty acid beta-oxidation.
Involvement in disease Defects in CPT1A are the cause of carnitine palmitoyltransferase 1A deficiency (CPT1AD) [MIM:255120]; also known as CPT-I deficiency or CPT1A deficiency. CPT1AD is a rare autosomal recessive metabolic disorder of long-chain fatty acid oxidation characterized by severe episodes of hypoketotic hypoglycemia usually occurring after fasting or illness. Onset is in infancy or early childhood.
Sequence similarities Belongs to the carnitine/choline acetyltransferase family.
Cellular localization Mitochondrion outer membrane.
Information by UniProt
Carnitine O palmitoyltransferase 1 liver isoform antibody
Carnitine O palmitoyltransferase I antibody
Carnitine O palmitoyltransferase I liver isoform antibody
Anti-CPT1A antibody - Carboxyterminal end images
Western blot - CPT1A antibody - Carboxyterminal end (ab71466)
Anti-CPT1A antibody - Carboxyterminal end (ab71466) at 1/100 dilution + Y79 cell line lysate at 35 µg Predicted band size : 88 kDa Observed band size : 90 kDa ( why is the actual band size different from the predicted?) Additional bands at : 46 kDa,60 kDa,70 kDa. We are unsure as to the identity of these extra bands.
References for Anti-CPT1A antibody - Carboxyterminal end (ab71466)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"