Anti-CRB2 antibody (ab126373)
Key features and details
- Rabbit polyclonal to CRB2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CRB2 antibody
See all CRB2 primary antibodies -
Description
Rabbit polyclonal to CRB2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence (RWDDGLRHLV MLSFGPDQLQ DLGQHVHVGG RLLAADSQPW GGPFRGCLQD LRLDGCHLPF FPLPLDNSSQ PSELGGRQSW NLT), corresponding to internal amino acids of Human CRB2
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Positive control
- IHC-P: Human retina, human kidney, human placenta tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126373 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
May play a role in polarized cells morphogenesis. -
Tissue specificity
Expressed in retina, fetal eye and brain. Also expressed in kidney, ARPE-19 and RPE/choroid cell lines, and at low levels in lung, placenta, and heart. -
Sequence similarities
Belongs to the Crumbs protein family.
Contains 15 EGF-like domains.
Contains 3 laminin G-like domains. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 286204 Human
- Omim: 609720 Human
- SwissProt: Q5IJ48 Human
- Unigene: 710092 Human
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Alternative names
- Crb2 antibody
- CRUM2_HUMAN antibody
- Crumbs homolog 2 (Drosophila) antibody
see all
Images
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Immunohistochemical analysis of human eye tissue (retina) labelling CRB2 in outer limiting membrane with ab126373 at 1/50 dilution.
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Immunohistochemical analysis of human placenta tissue labelling CRB2 in membrane of trophoblastic cells with ab126373 at 1/50 dilution.
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Immunohistochemical analysis of human kidney tissue labelling CRB2 in membrane of cells in glomeruli with ab126373 at 1/50 dilution.
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Immunohistochemical analysis of human Fallopian tube tissue labelling CRB2 in apical membrane of glandular cells with ab126373 at 1/50 dilution.
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Immunohistochemical analysis of human cerebral cortex labelling CRB2 in cytoplasm of neuronal cells with ab126373 at 1/50 dilution.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab126373 has not yet been referenced specifically in any publications.