Overview

  • Product nameAnti-CRB3 antibody
    See all CRB3 primary antibodies
  • Description
    Mouse polyclonal to CRB3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length CRB3 protein (Human)

  • Positive control
    • CRB3 transfected 293T cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab67618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 13 kDa (predicted molecular weight: 13 kDa).

Target

  • FunctionInvolved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions.
  • Tissue specificityPreferentially expressed in epithelial tissues. Expressed at high levels in lung, kidney, retina, colon and mammary glands. Expressed at moderate levels in liver, spleen, pancreas, placenta and prostate.
  • DomainThe PDZ-binding motif is involved in the interactions with PARD6A and MPP5.
  • Cellular localizationApical cell membrane. Cell junction > tight junction. Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • CRB3 antibody
    • CRUM3_HUMAN antibody
    • crumbs homolog 3 (Drosophila) antibody
    • Crumbs protein homolog 3 antibody
    • crumbs, Drosophila, homolog of, 3 antibody
    • PRO1158 antibody
    • protein crumbs homolog 3 antibody
    • UNQ588 antibody
    see all

Anti-CRB3 antibody images

  • All lanes : Anti-CRB3 antibody (ab67618) at 1/500 dilution

    Lane 1 : CRB3 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 13 kDa
    Observed band size : 13 kDa

References for Anti-CRB3 antibody (ab67618)

ab67618 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. The antibody ab67618 is a mouse polyclonal raised against full-length recombinant human CRB3. Alignment of the human protein with the mouse and rat proteins returns this result: Human - UniProt Q9BUF7 Mouse - UniProt...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"