Overview

  • Product nameAnti-Creatine kinase MT antibody
    See all Creatine kinase MT primary antibodies
  • Description
    Rabbit polyclonal to Creatine kinase MT
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A KLH conjugated synthetic peptide selected within aa 1-100 of human CKMT1 (creatine kinase, mitochondrial 1A).

  • Positive control
    • Mouse colon tissue lysate and ZR-75-1 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab38278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Detects a band of approximately 47, 52 kDa (dependent of cell lysate) (predicted molecular weight: 47 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceCreatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
    • Cellular localizationCell Membrane and Mitochondrial
    • Database links
    • Alternative names
      • Acidic type mitochondrial creatine kinase antibody
      • CKMT antibody
      • CKMT1 antibody
      • CKMT1A antibody
      • CKMT1B antibody
      • Creatine kinase mitochondrial 1 ubiquitous antibody
      • Creatine kinase U type, mitochondrial antibody
      • Creatine kinase ubiquitous mitochondrial antibody
      • Creatine kinase, mitochondrial 1 (ubiquitous) antibody
      • Creatine kinase, mitochondrial 1A antibody
      • Creatine kinase, mitochondrial 1B antibody
      • Mia CK antibody
      • U MtCK antibody
      • Ubiquitous mitochondrial creatine kinase antibody
      • UMTCK antibody
      see all

    Anti-Creatine kinase MT antibody images

    • All lanes : Anti-Creatine kinase MT antibody (ab38278) at 1/100 dilution

      Lane 1 : mouse colon tissue lysate
      Lane 2 : ZR-75-1 cell lysate


      Predicted band size : 47 kDa
      Observed band size : 47 and 52 kDa (why is the actual band size different from the predicted?)

    References for Anti-Creatine kinase MT antibody (ab38278)

    ab38278 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"