Overview

  • Product nameAnti-Creatine kinase MT antibody
    See all Creatine kinase MT primary antibodies
  • Description
    Mouse monoclonal to Creatine kinase MT
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: GVHIKLPLLS KDSRFPKILE NLRLQKRGTG GVDTAATGGV FDISNLDRLG KSEVELVQLV IDGVNYLIDC ERRLERGQDI RIPTPVIHTK H, corresponding to amino acids 327-418 of Human Creatine kinase MT (NP_066270)

  • Positive control
    • A431 Human epithelial carcinoma cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab93029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 46 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceCreatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
    • Cellular localizationCell Membrane and Mitochondrial
    • Database links
    • Alternative names
      • Acidic type mitochondrial creatine kinase antibody
      • CKMT antibody
      • CKMT1 antibody
      • CKMT1A antibody
      • CKMT1B antibody
      • Creatine kinase mitochondrial 1 ubiquitous antibody
      • Creatine kinase U type, mitochondrial antibody
      • Creatine kinase ubiquitous mitochondrial antibody
      • Creatine kinase, mitochondrial 1 (ubiquitous) antibody
      • Creatine kinase, mitochondrial 1A antibody
      • Creatine kinase, mitochondrial 1B antibody
      • Mia CK antibody
      • U MtCK antibody
      • Ubiquitous mitochondrial creatine kinase antibody
      • UMTCK antibody
      see all

    Anti-Creatine kinase MT antibody images

    • Anti-Creatine kinase MT antibody (ab93029) at 5 µg/ml + A-431 cell lysate at 50 µg

      Predicted band size : 46 kDa
    • Anti-Creatine kinase MT antibody (ab93029) at 5 µg/ml + Immunogen at 0.2 µg

      Predicted band size : 46 kDa

    References for Anti-Creatine kinase MT antibody (ab93029)

    ab93029 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab93029.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"