Overview

  • Product nameAnti-Creatine kinase MT antibody
    See all Creatine kinase MT primary antibodies
  • Description
    Rabbit polyclonal to Creatine kinase MT
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow, Dog, Pig, Monkey, Zebrafish
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 63 and 297 of Human Creatine kinase MT (NP_066270)

  • Positive control
    • H1299 and HeLaS3 whole cell lysate; 293T and HepG2 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab97481 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.

Target

  • RelevanceCreatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
  • Cellular localizationCell Membrane and Mitochondrial
  • Database links
  • Alternative names
    • Acidic type mitochondrial creatine kinase antibody
    • CKMT antibody
    • CKMT1 antibody
    • CKMT1A antibody
    • CKMT1B antibody
    • Creatine kinase mitochondrial 1 ubiquitous antibody
    • Creatine kinase U type, mitochondrial antibody
    • Creatine kinase ubiquitous mitochondrial antibody
    • Creatine kinase, mitochondrial 1 (ubiquitous) antibody
    • Creatine kinase, mitochondrial 1A antibody
    • Creatine kinase, mitochondrial 1B antibody
    • Mia CK antibody
    • U MtCK antibody
    • Ubiquitous mitochondrial creatine kinase antibody
    • UMTCK antibody
    see all

Anti-Creatine kinase MT antibody images

  • All lanes : Anti-Creatine kinase MT antibody (ab97481) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa S3 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 47 kDa

References for Anti-Creatine kinase MT antibody (ab97481)

ab97481 has not yet been referenced specifically in any publications.

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