• Product nameAnti-CRELD1 antibody
    See all CRELD1 primary antibodies
  • Description
    Rabbit polyclonal to CRELD1
  • Tested applicationsSuitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    A 14-22 amino acid region within synthetic peptide: EGGYRCICAE GYKQMEGICV KEQIPESAGF FSEMTEDELV VLQQMFFGII, corresponding to C terminal amino acids 325-374 of Human CRELD1

  • Positive control
    • HepG2 cell lysate or human kidney tissue.



Our Abpromise guarantee covers the use of ab65557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1:312500.

WB Use a concentration of 5 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.


  • Tissue specificityHighly expressed in fetal lung, liver, kidney, adult heart, brain and skeletal muscle. Weakly expressed in placenta, fetal brain, and adult lung, liver, kidney and pancreas.
  • Involvement in diseaseDefects in CRELD1 may be the cause of susceptibility to atrioventricular septal defect type 2 (AVSD2) [MIM:606217]. AVSD is a spectrum of cardiac malformations that result in a persistent common atrioventricular canal. The complete form of AVSD involves underdevelopment of the lower part of the atrial septum and the upper part of the ventricular septum. A less severe form, known as partial AVSD or ostium primum atrial septal defect has a deficiency of the atrial septum. Complete AVSD are clinically apparent at birth, whereas less severe forms, such as an isolated cleft mitral valve or small defects of the atrial or ventricular septa may go undetected.
  • Sequence similaritiesBelongs to the CRELD family.
    Contains 2 EGF-like domains.
    Contains 2 FU (furin-like) repeats.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Atrioventricular septal defect 2 antibody
    • AVSD2 antibody
    • CIRRIN antibody
    • CREL1_HUMAN antibody
    • CRELD1 antibody
    • Cysteine rich with EGF like domains 1 antibody
    • Cysteine-rich with EGF-like domain protein 1 antibody
    • DKFZP566D213 antibody
    see all

Anti-CRELD1 antibody images

  • All lanes : Anti-CRELD1 antibody (ab65557) at 5 µg/ml

    Lane 1 : MW marker
    Lane 2 : HepG2 cell lysate at 10 µg

    Lane 2 : HRP conjugated anti-Rabbit IgG at 50000

    Predicted band size : 45 kDa
    Observed band size : 45 kDa
    Additional bands at : 59 kDa. We are unsure as to the identity of these extra bands.
  • Ab65557 (4ug/ml) staining human CRELD1 in human kidney tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

    Epithelial cells of the renal tubule (indicated by arrows) were positively stained.

References for Anti-CRELD1 antibody (ab65557)

ab65557 has not yet been referenced specifically in any publications.

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