Anti-CrkL antibody [Y244] (ab32018)

Overview

  • Product nameAnti-CrkL antibody [Y244]
    See all CrkL primary antibodies
  • Description
    Rabbit monoclonal [Y244] to CrkL
  • Specificityab32018 recognises CrkL (Crk-like)protein.
  • Tested applicationsSuitable for: WB, IHC-P, ICC, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in the second SH3 domain and near C terminus of human Crk like protein

  • Positive control
    • K562 cell lysate, human metastatic lung carcinoma
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab32018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 36 kDa (predicted molecular weight: 33 kDa).
IHC-P Use at an assay dependent concentration.
ICC 1/50.
IP 1/10.

Target

  • FunctionMay mediate the transduction of intracellular signals.
  • Sequence similaritiesBelongs to the CRK family.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt
  • Database links
  • Alternative names
    • Crk L antibody
    • Crk like protein antibody
    • Crk-like protein antibody
    • Crkl antibody
    • CRKL_HUMAN antibody
    • Crkol antibody
    • HGNC:2363 antibody
    • Oncogene CrkL antibody
    • V crk avian sarcoma virus CT10 oncogene homolog like antibody
    • v crk sarcoma virus CT10 oncogene homolog (avian) like antibody
    • V crk sarcoma virus CT10 oncogene homolog avian like antibody
    see all

Anti-CrkL antibody [Y244] images

  • Anti-CrkL antibody [Y244] (ab32018) at 1/500 dilution + K562 cell lysate

    Predicted band size : 33 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • ab32018, at a 1/50 dilution, staining human Crk in metastatic lung carcinoma by Immunohistochemistry, in paraffin embedded tissue

References for Anti-CrkL antibody [Y244] (ab32018)

ab32018 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. I have confirmed that neither of these two anti-CrkL antibodies, ab32018 or ab32126, bind within the region a.a. 123 - 183 (the first SH3 domain). I apologize but it doesn't look like any of the anti-CrkL ant...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"