Overview

  • Product name
  • Description
    Goat polyclonal to CRLS1
  • Host species
    Goat
  • Specificity
    ab179943 is expected to recognise both isoforms (Q9UJA2-1 and Q9UJA2-2).
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human CRLS1 aa 161-174 (internal sequence) (Cysteine residue).
    Sequence:

    RSALGSALDPLADK


    Database link: Q9UJA2

  • Positive control
    • Human kidney tissue, HEK293 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab179943 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.2 - 0.6 µg/ml.

Target

  • Function
    Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  • Tissue specificity
    Highly expressed in tissues such as heart, skeletal muscle and liver.
  • Sequence similarities
    Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 0610009I22Rik antibody
    • 4930557M15Rik antibody
    • 5730490M08 antibody
    • C20orf155 antibody
    • Cardiolipin synthase 1 antibody
    • Cardiolipin synthase antibody
    • CLS antibody
    • CLS1 antibody
    • CRLS1 antibody
    • CRLS1_HUMAN antibody
    • dJ967N21.6 antibody
    • GCD10 antibody
    • OTTMUSP00000016677 antibody
    • Protein GCD10 homolog antibody
    • RGD1311037 antibody
    • RP23-77H16.4 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue, labeling CRLS1 with ab179943 at 5 µg/ml.

  • Anti-CRLS1 antibody (ab179943) at 0.2 µg/ml + HEK293 cell lysate in RIPA buffer at 35 µg

    Developed using the ECL technique.


    Primary incubation was 1 hour.

References

ab179943 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab179943.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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