Overview

  • Product name
  • Description
    Rabbit polyclonal to CRMP2
  • Tested applications
    Suitable for: ELISA, WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region from the C-Terminus of Human CRMP2 (NP_001377.1).

  • Positive control
    • A549 cell extracts (treated with EGF 200ng/ml for 30min); Human Brain (Cortex), Colon (Peripheral Nerve) and Pancreas (Peripheral Nerve) tissues; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab118842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/500 - 1/1000. Predicted molecular weight: 62 kDa.
IHC-P Use a concentration of 10 µg/ml.
ICC/IF 1/100 - 1/500.

Target

  • Function
    Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • Post-translational
    modifications
    3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Collapsin response mediator protein 2 antibody
    • Collapsin response mediator protein antibody
    • Collapsin response mediator protein hCRMP 2 antibody
    • CRAM antibody
    • CRMP 2 antibody
    • CRMP-2 antibody
    • CRMP2 antibody
    • DHPRP 2 antibody
    • DHPRP2 antibody
    • Dihydropyrimidinase 2 antibody
    • Dihydropyrimidinase like 2 antibody
    • Dihydropyrimidinase like 2 long form antibody
    • Dihydropyrimidinase related protein 2 antibody
    • Dihydropyrimidinase-related protein 2 antibody
    • DPYL 2 antibody
    • DPYL2 antibody
    • DPYL2_HUMAN antibody
    • DPYSL 2 antibody
    • Dpysl2 antibody
    • DRP-2 antibody
    • DRP2 antibody
    • Musunc 33 antibody
    • Musunc33 antibody
    • N2A3 antibody
    • TOAD 64 antibody
    • TOAD64 antibody
    • ULIP 2 protein antibody
    • ULIP-2 antibody
    • Ulip2 antibody
    • Unc-33-like phosphoprotein 2 antibody
    see all

Images

  • All lanes : Anti-CRMP2 antibody (ab118842) at 1/500 dilution

    Lane 1 : A549 cell extracts, treated with EGF (200ng/ml for 30min)
    Lane 2 : A549 cell extracts, treated with EGF (200ng/ml for 30min) with synthesized peptide


    Predicted band size : 62 kDa
  • ab118842, at 10 µg/ml, staining CRMP2 in Formalin-fixed, Paraffin-embedded Human Brain, cortex tissue by Immunohistochemistry.
  • ab118842, at 10 µg/ml, staining CRMP2 in Formalin-fixed, Paraffin-embedded Human Colon, peripheral Nerve tissue by Immunohistochemistry.
  • ab118842, at 10 µg/ml, staining CRMP2 in Formalin-fixed, Paraffin-embedded Human Pancreas, peripheral Nerve tissue by Immunohistochemistry.
  • Immunofluorescence analysis of CRMP2 staining in HeLa cells, using ab118842 at 1/100 dilution. The image on the image is treated with the synthesized peptide.

References

ab118842 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Unfortunately, we are not able to release the immunogen sequences of these particular antibodies; we consider it is a proprietary information.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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