• Product name
  • Description
    Rabbit polyclonal to CRMP2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Chicken, Cow, Xenopus laevis, Zebrafish, Orangutan
  • Immunogen

    Synthetic peptide:


    conjugated to KLH, corresponding to amino acids 476-493 of Human CRMP2

  • Positive control
    • Hela whole cell lysate; mouse brain extract



Our Abpromise guarantee covers the use of ab62661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).


  • Function
    Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • Tissue specificity
  • Sequence similarities
    Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • Post-translational
    3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Collapsin response mediator protein 2 antibody
    • Collapsin response mediator protein antibody
    • Collapsin response mediator protein hCRMP 2 antibody
    • CRAM antibody
    • CRMP 2 antibody
    • CRMP-2 antibody
    • CRMP2 antibody
    • DHPRP 2 antibody
    • DHPRP2 antibody
    • Dihydropyrimidinase 2 antibody
    • Dihydropyrimidinase like 2 antibody
    • Dihydropyrimidinase like 2 long form antibody
    • Dihydropyrimidinase related protein 2 antibody
    • Dihydropyrimidinase-related protein 2 antibody
    • DPYL 2 antibody
    • DPYL2 antibody
    • DPYL2_HUMAN antibody
    • DPYSL 2 antibody
    • Dpysl2 antibody
    • DRP-2 antibody
    • DRP2 antibody
    • Musunc 33 antibody
    • Musunc33 antibody
    • N2A3 antibody
    • TOAD 64 antibody
    • TOAD64 antibody
    • ULIP 2 protein antibody
    • ULIP-2 antibody
    • Ulip2 antibody
    • Unc-33-like phosphoprotein 2 antibody
    see all

Anti-CRMP2 antibody images

  • All lanes : Anti-CRMP2 antibody (ab62661) at 1/10000 dilution

    Lane 1 : Mouse brain (S1 fraction)
    Lane 2 : Rat brain (S1 fraction)
    Lane 3 : HeLa cells
    Lane 4 : HEK-293T cells transfected with human CRMP2
    Lane 5 : Untransfected HEK-293T cells
    Lane 6 : Mouse brain (S1 fraction): with CRMP2 immunizing peptide at 10 µg/ml

    Goat Anti-Rabbit IgG, Peroxidase conjugate
    Developed using the ECL technique

    Predicted band size : 63 kDa
    Observed band size : 63 kDa
  • All lanes : Anti-CRMP2 antibody (ab62661) at 1/10000 dilution

    Lane 1 : Cell lysate prepared from rat cortex.
    Lane 2 : to 10 : Rat hippocampal homogenates.

    Lysates/proteins at 5 µg per lane.

    Alexafluor 680 conjugated mouse polyclonal to rabbit at 1/5000 dilution

    Performed under reducing conditions.

    Predicted band size : 63 kDa
    Observed band size : 63 kDa

    Exposure time : 2 minutes

    This image is courtesy of an Abreview submitted by Dr Martin Broadstock

    See Abreview

References for Anti-CRMP2 antibody (ab62661)

This product has been referenced in:
  • Hori M  et al. PACAP38 differentially effects genes and CRMP2 protein expression in ischemic core and penumbra regions of permanent middle cerebral artery occlusion model mice brain. Int J Mol Sci 15:17014-34 (2014). WB ; Mouse . Read more (PubMed: 25257527) »
  • Braunschweig D  et al. Autism-specific maternal autoantibodies recognize critical proteins in developing brain. Transl Psychiatry 3:e277 (2013). Read more (PubMed: 23838888) »

See all 5 Publications for this product

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Abcam guarantees this product to work in the species/application used in this Abreview.
Western blot
Rat Cell lysate - whole cell (Hippocampal lysates - mouse)
Loading amount
5 µg
Hippocampal lysates - mouse
Gel Running Conditions
Reduced Denaturing (10% gel, 5 micrograms protein loaded)
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 20°C

Dr. Martin Broadstock

Verified customer

Submitted May 14 2009


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