Overview

  • Product nameAnti-CRMP4 antibody
    See all CRMP4 primary antibodies
  • Description
    Rabbit polyclonal to CRMP4
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 422 - 567 of Human CRMP4 (NM_001387).

  • Positive control
    • WB: Human fetal brain lysate IHC-P: Human fetal skeletal muscle

Properties

Applications

Our Abpromise guarantee covers the use of ab101009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 61 kDa (predicted molecular weight: 62 kDa).
IHC-P 1/100 - 1/500.

Target

  • FunctionNecessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
  • Tissue specificityMainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
  • Sequence similaritiesBelongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
  • Post-translational
    modifications
    Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
  • Cellular localizationCytoplasm. Cell projection > growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
  • Information by UniProt
  • Database links
  • Alternative names
    • Collapsin response mediator protein 4 antibody
    • Collapsin response mediator protein 4 long antibody
    • CRMP 4 antibody
    • CRMP-4 antibody
    • CRMP4 antibody
    • Dihydropyrimidinase like 3 antibody
    • Dihydropyrimidinase related protein 3 antibody
    • Dihydropyrimidinase-related protein 3 antibody
    • DPYL3_HUMAN antibody
    • DPYSL3 antibody
    • DRP 3 antibody
    • DRP-3 antibody
    • DRP3 antibody
    • LCRMP antibody
    • TUC4 antibody
    • ULIP 1 antibody
    • ULIP antibody
    • ULIP-1 antibody
    • ULIP1 antibody
    • UNc 33 like phosphoprotein 1 antibody
    • Unc 33 like phosphoprotein antibody
    • Unc-33-like phosphoprotein 1 antibody
    see all

Anti-CRMP4 antibody images

  • Anti-CRMP4 antibody (ab101009) at 1/1000 dilution + Human fetal brain lysate

    Predicted band size : 62 kDa
    Observed band size : 61 kDa (why is the actual band size different from the predicted?)
  • ab101009, at a 1/100 dilution, staining CRMP4 in formalin fixed, paraffin embedded Human fetal skeletal muscle. The image shows cytoplasmic staining of the antibody.

References for Anti-CRMP4 antibody (ab101009)

ab101009 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"