Overview

  • Product name
  • Description
    Rabbit polyclonal to CROP
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 200 and 250 of human CROP (NP_057508.2).

  • Positive control
    • Whole cell lysate from HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab80415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
  • Application notes
    IP: Use at 2 - 5 µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing.
    • Tissue specificity
      Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.
    • Sequence similarities
      Belongs to the Luc7 family.
    • Post-translational
      modifications
      Phosphorylated in vitro by SRPK1, SRPK2 and CLK1.
    • Cellular localization
      Nucleus speckle. The subnuclear localization is affected by cisplatin.
    • Information by UniProt
    • Database links
    • Alternative names
      • cAMP regulatory element-associated protein 1 antibody
      • Cisplatin resistance-associated overexpressed protein antibody
      • Cisplatin resistance-associated-overexpressed protein antibody
      • CRA antibody
      • CRE-associated protein 1 antibody
      • CREAP-1 antibody
      • CREAP1 antibody
      • CROP antibody
      • hLuc7A antibody
      • LC7L3_HUMAN antibody
      • LUC7 like 3 pre mRNA splicing factor antibody
      • Luc7-like protein 3 antibody
      • Luc7A antibody
      • LUC7L3 antibody
      • O48 antibody
      • OA48 18 antibody
      • Okadaic acid-inducible phosphoprotein OA48-18 antibody
      see all

    Images

    • Detection of human CROP in Immunoprecipitates of whole cell lysate from HeLa cells (1 mg for IP, 20% of IP loaded) using ab80415 at 3 µg/mg lysate for IP (lane 1). Lane 2 represents control IgG IP. Subsequent WB detection used ab80412 (which recognizes an upstream epitope) at 1 µg/ml.

    References

    ab80415 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab80415.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up