Overview

  • Product nameAnti-CRSP7 antibody [2216C1a]
    See all CRSP7 primary antibodies
  • Description
    Mouse monoclonal [2216C1a] to CRSP7
  • Tested applicationsSuitable for: WB, Dot blot, ChIPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment carrying 50-200 aa of human CRSP7

  • Positive control
    • Recombinant CRSP7 fragment.

Properties

Applications

Our Abpromise guarantee covers the use of ab50619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 37 kDa (predicted molecular weight: 65 kDa).
Dot blot Use at an assay dependent concentration.
ChIP Use at an assay dependent concentration. PubMed: 24466310

Target

  • FunctionComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • Sequence similaritiesBelongs to the Mediator complex subunit 26 family.
    Contains 1 TFIIS N-terminal domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activator recruited cofactor 70 kDa component antibody
    • Activator-recruited cofactor 70 kDa component antibody
    • ARC 70 antibody
    • ARC70 antibody
    • Cofactor required for Sp1 transcriptional activation subunit 7 antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7 (70kD) antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa antibody
    • CRSP 7 antibody
    • CRSP complex subunit 7 antibody
    • CRSP70 antibody
    • MED 26 antibody
    • Med26 antibody
    • MED26_HUMAN antibody
    • Mediator complex subunit 26 antibody
    • Mediator of RNA polymerase II transcription subunit 26 antibody
    • Transcriptional coactivator CRSP70 antibody
    see all

Anti-CRSP7 antibody [2216C1a] images

References for Anti-CRSP7 antibody [2216C1a] (ab50619)

This product has been referenced in:
  • Fowler T  et al. Regulation of MYC expression and differential JQ1 sensitivity in cancer cells. PLoS One 9:e87003 (2014). ChIP ; Human . Read more (PubMed: 24466310) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"