Overview

  • Product name
  • Description
    Rabbit polyclonal to CRSP7
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Chicken, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 543 - 593 of Human CRSP7 (NP_004822.2).

  • Positive control
    • Whole cell lysate from HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab114101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 5-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    • Sequence similarities
      Belongs to the Mediator complex subunit 26 family.
      Contains 1 TFIIS N-terminal domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Activator recruited cofactor 70 kDa component antibody
      • Activator-recruited cofactor 70 kDa component antibody
      • ARC 70 antibody
      • ARC70 antibody
      • Cofactor required for Sp1 transcriptional activation subunit 7 antibody
      • Cofactor required for Sp1 transcriptional activation, subunit 7 (70kD) antibody
      • Cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa antibody
      • CRSP 7 antibody
      • CRSP complex subunit 7 antibody
      • CRSP70 antibody
      • MED 26 antibody
      • Med26 antibody
      • MED26_HUMAN antibody
      • Mediator complex subunit 26 antibody
      • Mediator of RNA polymerase II transcription subunit 26 antibody
      • Transcriptional coactivator CRSP70 antibody
      see all

    Images

    • Rabbit anti-CRSP7 antibody, at 0.4 µg/ml, staining CRSP7 in HeLa whole cell lysate immunoprecipitated using ab114101 at 10 µg/mg lysate (1 mg for IP; 20% of IP loaded/lane). Detection: Chemiluminescence with an exposure time of 15 seconds.

    References

    ab114101 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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