Anti-CRTAM antibody [MM0204-21A9] (ab89171)

Overview

  • Product nameAnti-CRTAM antibody [MM0204-21A9]
    See all CRTAM primary antibodies
  • Description
    Mouse monoclonal [MM0204-21A9] to CRTAM
  • Tested applicationsSuitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human) (extracellular domain)

Properties

Applications

Our Abpromise guarantee covers the use of ab89171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 45 kDa.
Flow Cyt 1/50 - 1/200. ab18414-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • FunctionInteraction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
  • Tissue specificityIn the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. Strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in Purkinje neurons in cerebellum. Expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues.
  • Sequence similaritiesBelongs to the nectin family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD355 antibody
    • Class I MHC restricted T cell associated molecule antibody
    • Class-I MHC-restricted T-cell-associated molecule antibody
    • CRTAM antibody
    • CRTAM_HUMAN antibody
    • Cytotoxic and regulatory T cell molecule antibody
    • Cytotoxic and regulatory T-cell molecule antibody
    see all

References for Anti-CRTAM antibody [MM0204-21A9] (ab89171)

ab89171 has not yet been referenced specifically in any publications.

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