Overview

  • Product nameAnti-CRYZ antibody [2A9DD1]
    See all CRYZ primary antibodies
  • Description
    Mouse monoclonal [2A9DD1] to CRYZ
  • Tested applicationsSuitable for: ICC/IF, IP, In-Cell ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to CRYZ. Human liver mitochondria.

  • Positive control
    • HeLa cells; Human liver and HepG2 lysates.
  • General notes

    Product was previously marketed under the MitoSciences sub-brand.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab110310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 2 µg/ml. For 2 hours.
IP Use at an assay dependent dilution.
In-Cell ELISA Use at an assay dependent concentration.

Target

  • FunctionDoes not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
  • Tissue specificityOnly very low amounts in the lens.
  • Sequence similaritiesBelongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Crystallin zeta (quinone reductase) antibody
    • Crystallin zeta antibody
    • Cryz antibody
    • DKFZp779E0834 antibody
    • FLJ41475 antibody
    • NADPH:quinone reductase antibody
    • QOR_HUMAN antibody
    • Quinone oxidoreductase antibody
    • Zeta crystallin antibody
    • Zeta-crystallin antibody
    see all

Anti-CRYZ antibody [2A9DD1] images

  • Immunocytochemistry analysis using ab110310 at 2µg/ml staining CRYZ in HELa cells (4% paraformaldehyde fixed and 0.1% Triton X-100 permeabilized) followed by Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1 hour (green).
  • Using MitoSciences' standard immunoprecipitation protocol, ab110310 precipitates the 35kDa CRYZ protein from human liver and HepG2 lysate. Identity of this protein was confirmed by mass spectrometry. This gel was stained with silver nitrate.

References for Anti-CRYZ antibody [2A9DD1] (ab110310)

ab110310 has not yet been referenced specifically in any publications.

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