Overview

  • Product nameAnti-CRYZ antibody
    See all CRYZ primary antibodies
  • Description
    Rabbit polyclonal to CRYZ
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 216-265 (KGIDIIIEML ANVNLSKDLS LLSHGGRVIV VGSRGTIEIN PRDTMAKESS) of Human CRYZ (NP_001880).

  • Positive control
    • Human fetal liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab84569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionDoes not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
  • Tissue specificityOnly very low amounts in the lens.
  • Sequence similaritiesBelongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Crystallin zeta (quinone reductase) antibody
    • Crystallin zeta antibody
    • Cryz antibody
    • DKFZp779E0834 antibody
    • FLJ41475 antibody
    • NADPH:quinone reductase antibody
    • QOR_HUMAN antibody
    • Quinone oxidoreductase antibody
    • Zeta crystallin antibody
    • Zeta-crystallin antibody
    see all

Anti-CRYZ antibody images

  • Anti-CRYZ antibody (ab84569) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal liver lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
    Additional bands at : 40 kDa. We are unsure as to the identity of these extra bands.

References for Anti-CRYZ antibody (ab84569)

ab84569 has not yet been referenced specifically in any publications.

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