Application notesPeptide ELISA: Antibody detection limit dilution 1/16000.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 402 kDa.
Preliminary experiments in human brain (substantia nigra and hippocampus) lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceCSMD3 belongs to the CSMD family and contains fourteen CUB domains and twenty eight Sushi (CCP/SCR) domains. It is weakly expressed in most tissues, except in brain; expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. There are five named isoforms.
Cellular localizationMembrane; Single pass type I membrane protein.