Overview

  • Product nameAnti-CtBP1 antibody
    See all CtBP1 primary antibodies
  • Description
    Rabbit polyclonal to CtBP1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within C terminal amino acids 400-440 of Human CtBP1 (SwissProt Q13363).

  • Positive control
    • Human breast adenocarcinoma. Human islet cell tumor.

Properties

Applications

Our Abpromise guarantee covers the use of ab84371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Antigen exposure is recommended.
    Antigen exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.
    • Sequence similaritiesBelongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    • Post-translational
      modifications
      The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.
      ADP-ribosylated; when cells are exposed to brefeldin A.
      Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • BARS antibody
      • brefeldin A- ribosylated substrate antibody
      • C terminal binding protein 1 antibody
      • C-terminal-binding protein 1 antibody
      • CTBP antibody
      • CtBP1 antibody
      • CTBP1_HUMAN antibody
      • MGC104684 antibody
      see all

    Anti-CtBP1 antibody images

    • ab84371 at 1/100, staining human CtBP1 in a section of human breast adenocarcinoma by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
    • ab84371 at 1/100, staining human CtBP1 in a section of human islet cell tumor by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

    References for Anti-CtBP1 antibody (ab84371)

    ab84371 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"