Overview

  • Product name
  • Description
    Rabbit polyclonal to CTDSPL
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids 4-34 of Human CTDSPL (NP_001008393.1 , NP_005799.2).

  • Positive control
    • HeLa cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 31 kDa.

Target

  • Function
    Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
  • Tissue specificity
    Expression is restricted to non-neuronal tissues.
  • Sequence similarities
    Contains 1 FCP1 homology domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • C3orf8 antibody
    • Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3 antibody
    • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like antibody
    • CTD small phosphatase-like protein antibody
    • CTDSL_HUMAN antibody
    • CTDSP-like antibody
    • Ctdspl antibody
    • hYA22 antibody
    • N-like protein antibody
    • NIF-like protein antibody
    • NLI-interacting factor 1 antibody
    • Nuclear LIM interactor-interacting factor 1 antibody
    • Protein YA22 antibody
    • RB protein serine phosphatase from chromosome 3 antibody
    • RBSP3 antibody
    • SCP3 antibody
    • Small C-terminal domain phosphatase 3 antibody
    • Small CTD phosphatase 3 antibody
    see all

Images

  • Anti-CTDSPL antibody (ab106973) at 1/100 dilution + HeLa cell lysate at 35 µg

    Predicted band size : 31 kDa

References

ab106973 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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