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CTGF protein (Mouse) (ab7861)

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Overview

Product name

CTGF protein (Mouse)
See all CTGF products (4) ...

Expression host

E. coli

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Concentration

Concentration information loading...

Sequence notes

Amino acids 223-348 of mouse CTGF.

Research areas

Immunology >> Secreted Molecules >> CCN Family
Cardiovascular >> Angiogenesis >> Growth Factors >> Other

Applications

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Our Abpromise guarantee covers the use of ab7861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

This peptide can be used with studies using ab6992.

Protein info

Function

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Tissue specificity

Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.

Sequence similarities

Belongs to the CCN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain.

Cellular localization

Secreted > extracellular space > extracellular matrix. Secreted.

Target information above from: UniProt accessionP29279 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for CTGF protein (Mouse) (ab7861)

ab7861 has not yet been referenced specifically in any publications.

Publishing research using ab7861? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"