• Product name
  • Description
    Rabbit polyclonal to CTHRC1
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Peptide corresponding to the C-terminal of CTHRC1 protein (Human).

  • Positive control
    • KZ-28 cells MMRU cells PMWK cells



Our Abpromise guarantee covers the use of ab54181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 27 kDa (predicted molecular weight: 27 kDa).
ELISA 1/2000 - 1/5000.
IHC-P Use at an assay dependent concentration.


  • Function
    May act as a negative regulator of collagen matrix deposition.
  • Tissue specificity
    Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells.
  • Sequence similarities
    Contains 1 collagen-like domain.
  • Post-translational
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Collagen triple helix repeat containing 1 antibody
    • Collagen triple helix repeat containing protein 1 antibody
    • Collagen triple helix repeat-containing protein 1 antibody
    • CTHR1_HUMAN antibody
    • Cthrc1 antibody
    • NMTC1 protein antibody
    • Protein NMTC1 antibody
    see all

Anti-CTHRC1 antibody images

  • Immunohistochemistry analysis of melanoma tissues using ab54181. Melanoma in situ (MIS) are negative, primary melanoma (PM) are positive and metastatic melanoma (MM) are strongly positive.

References for Anti-CTHRC1 antibody (ab54181)

This product has been referenced in:
  • Eriksson J  et al. Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression. Oncotarget 7:15065-92 (2016). WB, IHC . Read more (PubMed: 26918341) »
  • Kharaishvili G  et al. Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study. J Clin Pathol : (2011). IHC-P ; Human . Read more (PubMed: 21742751) »

See all 2 Publications for this product

Product Wall

Thank you for your reply.

I have recieved the general WB testing protocol used by our source for this antibody. Please note this is a guideline only, and may require some individual optimization.
I hope this will be helpful and look for...

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Thank you for contacting us.

As indicated on the datasheet (http://www.abcam.com/ab54181), the positive controls are melanomacell lines (KZ-28, MMRU, PMWK).
We have the following product your customer may be interested in : Melanoma (Hu...

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Thank you for taking time to complete our questionnaire. I am sorry to hear that this antibody is not providing satisfactory results. The details provided will enable us to investigate this case and will provide us with vital information for monitoring...

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Thank you for taking the time to contact us. Your enquiry has been forwarded to me as my colleage Anja is currently away from the office. I am sorry to hear you have had difficulty obtaining satisfactory results from this antibody.

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