Overview

  • Product nameAnti-CTHRC1 antibody
    See all CTHRC1 primary antibodies
  • Description
    Rabbit polyclonal to CTHRC1
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Peptide corresponding to the C-terminal of CTHRC1 protein (Human).

  • Positive control
    • KZ-28 cells MMRU cells PMWK cells

Properties

Applications

Our Abpromise guarantee covers the use of ab54181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 27 kDa (predicted molecular weight: 27 kDa).
ELISA 1/2000 - 1/5000.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionMay act as a negative regulator of collagen matrix deposition.
  • Tissue specificityIsoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells.
  • Sequence similaritiesContains 1 collagen-like domain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Collagen triple helix repeat containing 1 antibody
    • Collagen triple helix repeat containing protein 1 antibody
    • Collagen triple helix repeat-containing protein 1 antibody
    • CTHR1_HUMAN antibody
    • Cthrc1 antibody
    • NMTC1 protein antibody
    • Protein NMTC1 antibody
    see all

Anti-CTHRC1 antibody images

  • Immunohistochemistry analysis of melanoma tissues using ab54181. Melanoma in situ (MIS) are negative, primary melanoma (PM) are positive and metastatic melanoma (MM) are strongly positive.

References for Anti-CTHRC1 antibody (ab54181)

This product has been referenced in:
  • Kharaishvili G  et al. Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study. J Clin Pathol : (2011). IHC-P ; Human . Read more (PubMed: 21742751) »

See 1 Publication for this product

Product Wall

Thank you for your reply.

I have recieved the general WB testing protocol used by our source for this antibody. Please note this is a guideline only, and may require some individual optimization.
I hope this will be helpful and look for...

Read More

Thank you for contacting us.

As indicated on the datasheet (http://www.abcam.com/ab54181), the positive controls are melanomacell lines (KZ-28, MMRU, PMWK).
We have the following product your customer may be interested in : Melanoma (Hu...

Read More

Thank you for taking time to complete our questionnaire. I am sorry to hear that this antibody is not providing satisfactory results. The details provided will enable us to investigate this case and will provide us with vital information for monitoring...

Read More

Thank you for taking the time to contact us. Your enquiry has been forwarded to me as my colleage Anja is currently away from the office. I am sorry to hear you have had difficulty obtaining satisfactory results from this antibody.

I would l...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"